Background The redundant extracellular matrix (ECM) within tumor microenvironment (TME) such as hyaluronic acid (HA) often impairs intratumoral dissemination of antitumor drugs.Oncolytic viruses (OVs) are being studied extensively for cancer therapy either alone or in conjunction with chemotherapy and immunotherapy.Here, we designed a novel recombi
Analysis of seasonal and annual variations of aero-electric field at a midlatitudinal observatory Paratunka in Kamchatka was carried out for 1997-2016.Stable seasonal intervals of the highest and the lowest values are observed.Changeability of the annual trend of Vinegars aero-electric field in the near ground air layer at the observatory located i
Empirical research indicates that strategic alliances, like other organizational forms, emerge as an adaptive mechanism to market uncertainty, and their developments over time reflect the co-evolution of distinctive firm capabilities and of industry and market Musical Toys activities.Interestingly, most strategic alliances go through similar revolu
The purpose of the experiment was to study the influence of the laser beam in pulse Sheaths, Sleeves mode on metallic foils in order to obtain a spot weld.The welding process was carried out using the overlap weld method, using spot welds in various quantities.The Nd - YAG BLS 720 pulsed laser was used to conduct the experiment.The impact of the nu
PurposeTo systematically compare the efficacy and safety of lumbar total disc replacement (TDR) with the efficacy and safety of anterior lumbar interbody fusion (ALIF) for the Kit Donna treatment of lumbar degenerative disc disease (LDDD).MethodsThe electronic databases PubMed, Web of Science and the Cochrane Library were searched for the period fr